应该是：海藻糖 一种有甜味的双糖酶晶体，见于虫茧蜜和许多真菌中
Study of Torehalose: Trehalose, one of bicarbonate seen in desert plants, has been reported to protect cell membrane after long hours' preservation in lung transplantation. Methods: Hearts were harvested from 14 SD rats and connected to Langendorff's apparatus. After 20 minutes equilibration with Krebs-Henseleit buffer the hearts developed arrest by one of 2 different cardioplegic solution (20ml/kg): St. Thomas solution (n=8, Group A) and St. Thomas solution with 3% Torehalose (n=8, Group B). After 90 minutes' ischemia with intermittent infusion of the solution (10ml/kg) every 30 minutes the hearts had reperfusion. LV function was measured at the end of the equilibration, 5 and 15 minutes after the reperfusion. We also studied edema of the LV myocardium by relationship of weight of isolated hearts at the moment of harvesting and after 15 minutes' reperfusion. Results: Group B had better end-systolic pressure-volume relationship (ESPVR) than group A 5 minutes after the reperfusion. There was no difference in diastolic function as assessed by end-diastolic pressure-volume relationship (EDPVR) between the two groups. The rate of increase in weight of heart (weight after 15 minutes reperfusion / weight at harvesting) is 1.46±0.71 in Group A, and 1.14±0.37 in Group B (p<0.001). Pathological examinations revealed more edema of the LV myocardium in Group A than Group B. Conclusion: Trehalose can be given safely and it has potential benefits to preserve LV systolic function and to decrease myocardial edema after reperfusion.
